Pregnancy associated plasma protein-A (PAPP-A) as an early marker for the diagnosis of acute coronary syndrome
نویسندگان
چکیده
منابع مشابه
Comparison of pregnancy-associated plasma protein-A, troponin and creatine kinase-MB levels in acute coronary syndrome
Background: Early diagnosis and proper treatment of patient with acute coronary syndrome (ACS) and ischemic heart disease are important in determining prognosis, preventing adverse effects, and may even save lives. In this study, the level of pregnancy-associated plasma protein-A (PAPP-A) in ACS patients was compared with the control group, in addition to cardiac Troponin (cTn) and creatine kin...
متن کاملPregnancy-associated plasma protein A and copeptin as markers in the early diagnosis of acute coronary syndrome
Objective: To evaluate the combined detection of pregnancy-associated plasma protein A (PAPP-A) and copeptin as a diagnostic marker in patients with acute coronary syndrome (ACS). Methods: Serum levels of PAPP-A, copeptin, creatine kinase isoenzyme MB (CK-MB) and cardiac troponin I (cTnI) were detected within 3 hours after acute chest pain in 120 patients who were suspected of having ACS and in...
متن کاملImmunoassays developed for pregnancy-associated plasma protein-A (PAPP-A) in pregnancy may not recognize PAPP-A in acute coronary syndromes.
BACKGROUND Pregnancy-associated plasma protein-A (PAPP-A) concentrations are increased in the circulation of patients with acute coronary syndromes (ACS) and are associated with future adverse cardiac events. PAPP-A in ACS differs from PAPP-A in pregnancy in that PAPP-A in ACS is not complexed with the proform of eosinophil major basic protein (proMBP). We investigated the effect of antibody se...
متن کاملComment on immunoassays developed for pregnancy-associated plasma protein-A (PAPP-A) in pregnancy may not recognize PAPP-A in acute coronary syndromes.
1. Wald NJ, Cuckle H, Nanchahal K. Amniotic fluid acetylcholinesterase measurement in the prenatal diagnosis of open neural tube defects. Second Report of the Collaborative Acethylcholinesterase Study. Prenat Diagn 1989;9:813–29. 2. Canick JA, Kellner LH, Bombard AT. Prenatal screening for open neural tube defects. Lab Med 2003;23:385–94. 3. Hoffman A, Nimtz M, Getzlaff R, Conradt HS. “Brain ty...
متن کاملPregnancy-associated plasma protein-E (PAPP-E).
A full-length cDNA encoding a novel human protein was cloned from placenta cDNA. The corresponding 1542 amino acid protein sequence was termed 'pregnancy-associated plasma protein-E' (PAPP-E) as it shows a 62% homology to the human pregnancy-associated plasma protein-A (PAPP-A) that is a diagnostic marker for trisomies, especially Down syndrome. The conserved domain structure contains five moti...
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ژورنال
عنوان ژورنال: Indian Heart Journal
سال: 2012
ISSN: 0019-4832
DOI: 10.1016/s0019-4832(12)60049-2